Why not run it more? Because it is extremely detrimental to your defense.
For many years, I looked at the ten fastest offenses, the ten slowest offenses, and the ranking of each of their defenses. Every year, the fastest offenses tended to have some of the very worst defenses in the country. During those years, the fastest offenses routinely included Marshall, Arizona, Baylor, Cal, Texas Tech, Houston, and to a slower extent, Oregon.
During those years, some of the twenty worst defenses in the country included Baylor, Cal, Arizona, Tech, and Cal.
There is a very strong relationship between fast tempo offenses and productivity of that team’s own defense. If you want your team to go fast in order to give them an advantage, expect your defense to suffer.
Based simply on stats, an offense that put up over 500 yards and 31 points doesn’t seem to be blamed compared to a defense that gave up over 400 and 40 points. Of course, turnovers deep in your own territory and/or special teams play can be a reason for that, but blaming the OC for this game? Crazy.